Soumik Siddhanta

Soumik Siddhanta

Assistant Professor

Born: Kolkata, West Bengal
Integrated M.S. - Ph.D. (Prof. Chandrabhas Narayana), Jawaharlal Nehru Centre for Advanced Scientific Research, India, 2007-2014.
Post Doc (2015-2019): Johns Hopkins University, USA (Prof. Ishan Barman)
Assistant Professor: Indian Institute of Technology Delhi, November 2019-present.

Group Webpage

Research Interests

Our research focusses on developing integrative photonics solutions to complex problems in biological research and medical diagnosis. The research in our group is highly inter-disciplinary at the interface of physical chemistry, materials science, and biology. The primary aim is to harness the potent combination of the engineered plasmonic nanoprobes and label-free plasmon-enhanced vibrational spectroscopy for diagnosis, imaging, manipulation, and control of biological structure and function. Our work involves molecular spectroscopy and imaging, fabrication of nanomaterials, developing optical and microscopic methods (label-free, light-sheet, Raman, fluorescence/confocal, and others) for studying biological processes and developing platforms for medical diagnostics.

Selected Publications

  1. Zufang Huang, Soumik Siddhanta....Ishan Barman. Rapid, label‐free optical spectroscopy platform for diagnosis of heparin‐induced thrombocytopenia. Angew. Chem. 2020, 59, 5972.
  2. Soumik Siddhanta, Sourav Bhattacharjee, Sabine M. Harrison, Dimitri Scholz, and Ishan Barman, I. Shedding Light on the Trehalose‐Enabled Mucopermeation of Nanoparticles with Label‐Free Raman Spectroscopy. Small, 2019, 15(33), 1901679.
  3. Soumik Siddhanta, Chao Zheng, Chandrabhas Narayana and Ishan Barman. An impediment to random walk: Trehalose microenvironment drives preferential endocytic uptake of plasmonic nanoparticles, Chem. Sci, 2016, 7, 3730.
  4. Soumik Siddhanta, Maciej S. Wróbel, Ishan Barman. Integration of protein tethering in a rapid and label-free SERS screening platform for drugs of abuse. Chem. Commun. 2016; 52(58):9016-9.
  5. Dhanasekaran Karthigeyan,* Soumik Siddhanta,* et al. SERS and MD simulation studies of a kinase inhibitor demonstrate the emergence of a potential drug discovery tool, Proc. Nat. Acad. of Sci, USA, 2014, 111 (29), 10416-10421.
  6. Soumik Siddhanta, Varun Thakur, Chandrabhas Narayana and S.M. Shivaprasad, “Universal metal-semiconductor hybrid nanostructured SERS substrate for biosensing”, ACS Appl. Mat. & Int. 2012, 4 (11), 5807-5812.