Indian Institute of Technology Delhi
New Aspects of Enantioselective Catalysis by Chiral Brønsted Acids and Bases
Dr. Masahiro Terada
Department of Chemistry, Tohoku University, Aoba-ku Sendai 980-8578, Japan
Date: January 11th 2018 (Thursday)
Time: 11 AM
Venue: Committee Room, Chemistry Department, 6th Floor
In my continuous efforts to broaden the scope of enantioselective catalysis by chiral phosphoric acids, I have focused on the development of enantioselective nucleophilic substitution reaction, instead of the common nucleophilic addition reactions. Enantio-convergent substitution reaction and parallel kinetic resolution of racemic substrates are introduced in my presentation. In addition, the development of chiral uncharged organosuperbase catalyst, a pseudo C2-symmetric bis(guanidino)iminophosphorane, has been demonstrated to expand the scope of pro-nucleophiles in organocatalytic approaches.