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B JAYARAM
Office

Department of Chemistry
MS-718
Multi-storey building
6th Floor
IIT Delhi
Hauz Khas, New Delhi 110016
Tel: +91 11 2659 1505
Fax: +91 11 2658 1102



Laboratory

Department of Chemistry
MS-733
IIT Delhi
Tel: +91 11 2659 6512
Fax: +91 11 2658 1102



PROFESSOR

Professor, Department of Chemistry & School of Biological Sciences, IIT Delhi. Coordinator, Supercomputing Facility for Bioinformatics and Computational Biology (SCFBio), IIT Delhi. Ph.D. from City University of New York (Mentor: Prof. D. L. Beveridge), 1982-1986. Post Doctoral Fellow at Columbia University (PI: Prof. Barry Honig), 1987-88. Senior Research Associate at Wesleyan University (PI: Prof. D. L. Beveridge) 1989-90. Faculty at Indian Institute of Technology Delhi, 1990-present.

E-mail: bjayaram

Group Webpage
Research Interests

Biomolecular modeling and simulation, Physico-chemical understanding of genomic DNA organization (Chemgenome), protein tertiary structure prediction via chemistry and informatics based methods (Bhageerath) and protein/DNA targeted computer aided drug discovery (Sanjeevini).

Selected Publications

1. B. Jayaram, and T. Jain, “The role of water in protein-DNA recognition”, Annu. Rev. Biophys. Biomol. Struct. 2004, 33, 343-361.
2. B. Jayaram, K. Bhushan, S. Shenoy, P. Narang, S. Bose, P. Agrawal, D. Sahu, V. Pandey, “Bhageerath: an energy based web-enabled computer software suite for limiting the search space of tertiary structures of small globular proteins”, Nucleic Acids Res., 2006, 34, 6195-6204.
3. S. Shaikh, B. Jayaram, “A swift all atom energy based computational protocol to predict DNA-Drug binding affinity and Tm”, J. Med. Chem., 2007, 50, 2240-2244.
4. G. Khandelwal and B. Jayaram, “DNA-water interactions distinguish messenger RNA genes from transfer RNA genes”, J. Am. Chem. Soc., 2012, 134, 8814–8816; DOI: 10.1021/ja3020956.

Group Members

Shashank Shekhar
Vandana Shekhar
Avinash Mishra
Abhilash Jayaraj
Ashutosh Shandilya
Anjali Soni
Rahul Kaushik
Ankita Singh
Debarati DasGupta
Samarpreet Chakraborty
Ruchika Bhat
Pradeep Pant
Amita Pathak
Akhilesh Mishra
Manpreet Singh

Information

For email suffix @chemistry.iitd.ac.in

Department of Chemistry, Indian Institute of Technology Delhi