B Jayaram



Professor, Department of Chemistry & School of Biological Sciences, IIT Delhi. Coordinator, Supercomputing Facility for Bioinformatics and Computational Biology (SCFBio), IIT Delhi.
Ph.D. from City University of New York (Mentor: Prof. D. L. Beveridge), 1982-1986. Post Doctoral Fellow at Columbia University (PI: Prof. Barry Honig), 1987-88. Senior Research Associate at Wesleyan University (PI: Prof. D. L. Beveridge) 1989-90. Faculty at Indian Institute of Technology Delhi, 1990-present.

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Research Interests

Biomolecular modeling and simulation, Physico-chemical understanding of genomic DNA organization (Chemgenome), protein tertiary structure prediction via chemistry and informatics based methods (Bhageerath) and protein/DNA targeted computer aided drug discovery (Sanjeevini).

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Selected Publications

  1. R. Kaushik, A. Singh, and B. Jayaram, “Where informatics lags, chemistry leads”, Biochemistry, 2018, 57, 503-506.
  2. A. Singh, A. Mishra, A. Khosravi, G. Khandelwal, and B. Jayaram, “Physico-chemical fingerprinting of RNA Genes”, Nucleic Acids Res., 2017, 45(7), e47.
  3. J. L. Nishikawa et al., “Inhibiting fungal multidrug resistance by disrupting an activator-mediator interaction”, Nature, 2016, 530, 485-489.
  4. B. Jayaram et al., “Sanjeevini: A Freely Accessible Web-Server for Target Directed Lead Molecule Discovery”, BMC Bioinformatics, 2012, 13 (Suppl 17):S7.
  5. B. Jayaram et al., “Bhageerath: an energy based web-enabled computer software suite for limiting the search space of tertiary structures of small globular proteins”, Nucleic Acids Res., 2006, 34, 6195-6204.
  6. B. Jayaram, and T. Jain, “The role of water in protein-DNA recognition”, Annu. Rev. Biophys. Biomol. Struct., 2004, 33, 343-361.


      Group Members

  • Shashank Shekhar
  • Vandana Shekhar
  • Abhilash Jayaraj
  • Rahul Kaushik
  • Ankita Singh
  • Ruchika Bhat
  • Pradeep Pant
  • Amita Pathak
  • Akhilesh Mishra
  • Manpreet Singh